CHPPC Module 36: Common Order Sets & Protocol Consults
Part 9: Mastering Clinical Workflows

Module 36: Common Order Sets & Protocol Consults: A Pharmacist’s Guide

This module provides a deep-dive masterclass into the most common pharmacist-driven protocols and high-stakes order sets, translating them from checklists into powerful clinical workflows.

From Prescriptions to Playbooks

In community practice, your expertise is centered on the individual prescription. In the hospital, your value is magnified as you become the manager of entire clinical pathways, often initiated by a single order: “Pharmacy to Dose,” “Consult Pharmacy,” or the activation of a complex order set. These are not just orders; they are delegations of trust, placing the full responsibility for managing a high-risk therapy squarely in your hands.

This is where a pharmacist transitions from a dispenser of medication to a manager of medicine. An “order set” for sepsis or a “protocol” for a heparin drip is a clinical playbook, and your job is to be the expert quarterback who executes that playbook flawlessly. You must know when to order labs, how to interpret the results, how to adjust doses on the fly, and how to communicate your plan to the entire team.

This module is your playbook for the playbooks. We will deconstruct the six most common and critical pharmacist-managed protocols and order sets. You will learn the “why” behind every step, master the calculations, anticipate the common pitfalls, and gain the confidence to manage these complex patients with the authority and expertise of a seasoned hospital pharmacist.

Module Outline: The Core Six Playbooks

We will dissect the six most common and clinically significant order sets and protocols you will manage daily.

The Vancomycin Protocol Consult

A masterclass in pharmacokinetic dosing. We will cover loading doses for sepsis, calculating AUC/MIC targets, timing troughs, adjusting for renal dysfunction, and handling common nursing queries.

The Weight-Based Heparin Protocol Consult

Navigating the complexities of therapeutic anticoagulation. This section covers initial bolus/drip calculations for VTE and ACS, interpreting aPTT results, managing the titration nomogram, and reversal strategies.

The Sepsis Order Set

A deep dive into one of the most time-critical order sets. We will focus on the pharmacist’s role in the “Surviving Sepsis” bundle: rapid antibiotic selection, fluid resuscitation, and vasopressor basics.

The Acute Stroke (TPA) Order Set

Handling a “Code Stroke.” This section provides a masterclass on the TPA (Alteplase) protocol: running the exclusion checklist, weight-based dose calculation (bolus vs. infusion), and critical blood pressure management.

The Alcohol Withdrawal (CIWA) Protocol

A guide to symptom-triggered therapy for alcohol withdrawal. We will cover the CIWA scoring tool, the role of benzodiazepines, adjunctive therapies (thiamine, folate), and managing refractory delirium tremens.

The Patient-Controlled Analgesia (PCA) Order Set

A high-risk workflow focusing on the pharmacist as the ultimate safety check. This section covers demand vs. basal dosing, opioid-naive vs. tolerant patients, and programming the five critical levers of a PCA order.