Section 25.6: Creating Your Personal “Blue Book”
Forging Your Pocket Brain: A Step-by-Step Guide to Building a High-Yield, Personalized Clinical Reference You’ll Actually Use.
Creating Your Personal “Blue Book”
The capstone project of your orientation: a curated, high-speed tool for daily practice.
25.6.1 The “Why”: From Generic Encyclopedia to Personal Field Guide
Throughout your training, you’ve become an expert at using comprehensive, evidence-based resources like Lexicomp, Micromedex, and clinical practice guidelines. These are the encyclopedias of our profession—vast, authoritative, and essential. However, in the fast-paced reality of daily hospital practice, you often don’t need an encyclopedia. You need a field guide. You need a tool that is rapid, curated, and customized to the unique ecosystem of your specific hospital.
This is the purpose of a personal “Blue Book”—a pocket-sized collection of the high-frequency, institution-specific information you need to do your job safely and efficiently. The term originates from the pocket manuals carried by medical residents, but the concept is a powerful tool for any new clinician. The act of creating this book is, in itself, one of the most powerful learning exercises you can undertake during your first month. It forces you to identify what information is truly important, to seek out the answers, and to organize them in a way that makes sense to you.
A well-made Blue Book doesn’t replace your primary drug information resources. It complements them. It becomes your external brain, your “cache” for the information you access a dozen times a day. It is the tool that will shave precious seconds off your workflow, boost your confidence in critical moments, and serve as a tangible symbol of your growing mastery of your new environment. This section is a detailed, step-by-step blueprint for building the best Blue Book you possibly can.
25.6.2 The Analogy: From a Generic GPS to a Custom, Annotated Map
A Deep Dive into the Analogy
Think of your standard drug information app (like Lexicomp) as a Generic GPS. It is an incredibly powerful and essential tool. It contains a map of the entire country, can calculate a route from any point A to any point B, and provides a wealth of generic information. It is your ultimate source of truth for navigation. However, it lacks local knowledge. It doesn’t know the gate code to that one specific community, the unlisted phone number for the best pizza place, the hidden shortcut that avoids the 5 PM traffic jam, or that the bridge on Elm Street is closed for construction this week. To get that information, you’d have to search for it separately each time.
A personal Blue Book is your Custom, Annotated Map. It is the map you create yourself after exploring a new city for a month. You don’t redraw the entire map of the country; you just add the high-yield, local knowledge that makes your daily life easier.
- You highlight the route from your apartment to the hospital.
- In the margin next to the hospital, you write down the direct phone number to the ED pharmacy and the pager number for the cardiology fellow.
- You circle the location of the best coffee shop near work.
- You draw a big red ‘X’ over the Elm Street bridge with the note “CLOSED UNTIL NOV!”
- You write down the gate code for your friend’s apartment complex.
You wouldn’t use this map to navigate to a new city three states away—you’d use the GPS for that. But for the 95% of your daily travel within your own city, your custom map is faster, more efficient, and contains vital information that the generic GPS simply doesn’t have. This is your Blue Book. It doesn’t contain the full monograph for vancomycin, but it has the specific dosing nomogram for your hospital’s protocol right on the front page.
Masterclass Part 1: The Philosophy and Tools of Construction
The Guiding Philosophy: High-Frequency & Hyper-Local
Before you write a single word, internalize the two laws of a useful Blue Book:
- The Law of High Frequency: If you don’t need the information at least once a day or a few times a week, it probably doesn’t belong in your Blue Book. This tool is for speed. It’s for the data you are constantly re-verifying.
- The Law of Hyper-Local Specificity: If the information is easily found in the first two screens of a Lexicomp search, it does not belong in your Blue Book. The primary purpose of this tool is to store institutional knowledge—the “our hospital” information that exists nowhere else. Your hospital’s specific heparin nomogram is a perfect entry. The half-life of lisinopril is a terrible entry.
Choosing Your Weapon: Physical vs. Digital vs. Hybrid
| Format | The Pros | The Cons | Best For… |
|---|---|---|---|
| Physical Notebook (e.g., small, hardcover notebook like a Moleskine or Field Notes) |
– Extremely fast access. – No battery/connectivity issues. – Jotting down notes is quick and discreet. – The physical act of writing aids memory. |
– Can be lost or damaged. – Cannot be searched. – Difficult to edit/reorganize pages. – Limited space. |
The minimalist who values speed above all. Excellent for phone numbers, quick algorithms, and daily to-do lists. |
| Digital App (e.g., OneNote, Evernote, Apple Notes on a smartphone) |
– Infinitely editable and expandable. – Searchable, which is a massive advantage. – Can be accessed on multiple devices. – Can store PDFs and screenshots of policies. |
– Slower to access (unlock phone, find app, open note). – Phone use can be perceived as unprofessional. – Battery dependent. – Risk of distraction from other apps. |
The organized tech-savvy pharmacist who wants a powerful, searchable, long-term knowledge base. |
| The Hybrid Approach (Recommended) | Using both a physical notebook and a digital app for their respective strengths. | The pragmatic professional who wants the best of both worlds. | |
The Hybrid Workflow
This is the system used by many of the most efficient clinicians:
- Use the Physical Notebook as your daily “Capture Device” and “Cache.” This is for jotting down quick notes, phone numbers you need today, and your daily to-do list. It contains the hyper-urgent, high-frequency data for the next 12 hours.
- Use the Digital App as your permanent “Knowledge Base.” Once a week, take 30 minutes to transfer the important, long-term information from your physical notebook into your organized digital app (e.g., OneNote). You transfer the important new protocol information into your “Protocols” section, the new phone number into your “Contacts” section, and then you can discard the daily scribbles.
This workflow gives you the speed of paper for in-the-moment tasks and the power of a searchable digital database for your long-term reference.
Masterclass Part 2: The Blue Book Blueprint — A Section-by-Section Build Guide
The following is a recommended “Table of Contents” for your Blue Book, whether physical or digital. We will now do a deep dive into what high-yield information belongs in each chapter.
Chapter 1: The Phone Book
Philosophy: Your single source of truth for contact information. Seconds spent searching for a number are wasted seconds. This should be the very first section of your book.
What to Include:
- Your Pharmacy: Main line, IV room direct line, Lead tech’s pager, Clinical Manager’s number.
- Your Core Nursing Units: The HUC’s direct line and the Charge Nurse’s mobile phone/Voalte number for each unit you cover. This is gold.
- Key Hospital Departments: Laboratory (Chemistry and Microbiology), Dialysis Unit, Emergency Department, Operating Room front desk, PACU.
- Key Clinical Services: The pager or mobile number for the on-call resident/fellow for common consult services (Cardiology, GI, ID, Nephrology).
- Your Preceptor(s) and Fellow Pharmacists: Their mobile numbers for quick questions.
Chapter 2: The Cookbook (High-Frequency Dosing)
Philosophy: Abstract the key decision-making elements from the long, official policies. You don’t need the whole recipe, just the ingredients and cooking times for the dishes you make every day.
Sample Page Layout: Vancomycin Protocol
| Indication | Target AUC/MIC | Target Trough |
| Standard (SSTI, etc.) | 400-600 | 15-20 mcg/mL |
| CNS/Endocarditis/PNA | 400-600 | 15-20 mcg/mL |
Loading Dose: 25-30 mg/kg (actual body weight, max 3g)
Empiric Maintenance Dose (CrCl > 90): 15-20 mg/kg q8-12h
Sample Page Layout: Renal Dosing “Top 10”
| Drug | Standard Dose | CrCl 30-50 | CrCl <30 | On Dialysis |
|---|---|---|---|---|
| Apixaban (A-Fib) | 5mg BID | 2.5mg BID (if 2/3 criteria) | Use w/ caution | 2.5mg BID |
| Enoxaparin (Tx) | 1mg/kg Q12H | 1mg/kg Q24H | Contraindicated | Contraindicated |
| Pip/Tazo (Zosyn) | 3.375g Q6H | 2.25g Q6H | 2.25g Q8H | 2.25g Q8H + post-HD |
| …and so on… |
Chapter 3: The Formulary Guide
Philosophy: Document the local exceptions and “pain points.” You don’t need the whole formulary, just the 10-15 drugs that cause 90% of the formulary-related interventions.
What to Include:
- The “Big 5” Restricted Antibiotics: List the top 5 antimicrobials that always need approval (e.g., Meropenem, Daptomycin, Ceftaroline, etc.) and the name/pager for the ID fellow you need to contact.
- Common Therapeutic Interchanges: Create a simple “They Order -> We Give” table.
- e.g., Esomeprazole -> Pantoprazole
- e.g., Rosuvastatin -> Atorvastatin
- e.g., Valsartan -> Losartan
- The “Never on Formulary” List: List the top 3-5 branded drugs that are commonly ordered but are never available, and their preferred alternatives. (e.g., “Brilinta (ticagrelor) -> Use clopidogrel or prasugrel”).
Chapter 4: The Lab Manual
Philosophy: Capture key lab values that are essential for medication management but that you might not have memorized yet.
Sample Page Layout: Therapeutic Drug Monitoring
| Drug | Therapeutic Range | Timing of Level | Key Toxicities |
|---|---|---|---|
| Digoxin (A-Fib) | 0.5-0.9 ng/mL | Trough, >12h post-dose | Bradycardia, Vision changes |
| Phenytoin | 10-20 mcg/mL (total) | Trough | Nystagmus, Ataxia |
| Valproic Acid | 50-100 mcg/mL | Trough | Hepatotoxicity, Thrombocytopenia |
| Carbamazepine | 4-12 mcg/mL | Trough | Leukopenia, Rash (SJS) |
Other High-Yield Entries:
- Antidote / Reversal Agent List: A quick table of Agent -> Indication -> Location (e.g., KCentra -> Warfarin reversal -> Central Pharmacy fridge).
- Lab Fishbones: Draw the blank diagrams for a Basic Metabolic Panel (BMP) and a Complete Blood Count (CBC) so you can quickly jot down values on your worksheet during rounds.