Section 1: Understanding Social Determinants of Health (SDOH)
A deep dive into the non-medical factors—like housing, transportation, and economic stability—that have a profound impact on patient outcomes, and how to identify these barriers within your own patient population.
Understanding Social Determinants of Health (SDOH)
Moving your focus from the prescription in the patient’s hand to the world on their shoulders.
20.1.1 The “Why”: Moving Beyond the Pill to the Person’s World
Consider Mr. Harris, a 68-year-old man with Type 2 diabetes, hypertension, and heart failure. He is a frequent visitor to your hospital’s emergency department, and his chart is flagged for high readmission risk. From a purely clinical and operational perspective, he is a complex case, a drain on resources, and a challenge to your hospital’s quality metrics. His medication adherence, according to pharmacy fill records, is abysmal. He frequently misses refills for his insulin, lisinopril, and furosemide. A traditional operational review might conclude that he needs more education, a simplified regimen, or perhaps a stern lecture on the importance of taking his medications.
But what if you learned that Mr. Harris lives on a fixed income of $900 a month? That after paying his rent, he has less than $200 left for utilities, food, and all of his medication copayments? What if you learned that the closest pharmacy that accepts his insurance is a 45-minute bus ride away, and the bus only runs twice a day? That his neighborhood has no grocery stores, only convenience stores, making a diabetic-friendly diet nearly impossible? That he has no family nearby and suffers from profound social isolation, leading to depression that saps his motivation to manage his complex diseases?
Suddenly, Mr. Harris’s “non-adherence” is not a personal failing; it is a predictable outcome of his environment. The barriers to his health are not clinical, but structural. This is the paradigm-shifting reality of the Social Determinants of Health (SDOH). The World Health Organization (WHO) defines SDOH as “the non-medical factors that influence health outcomes. They are the conditions in which people are born, grow, work, live, and age, and the wider set of forces and systems shaping the conditions of daily life.”
As a pharmacy leader, embracing this concept is not an act of charity; it is a strategic imperative. Decades of research have shown that medical care itself is a surprisingly small driver of overall health outcomes. The work you do within the four walls of your pharmacy or hospital, while critically important, is only one piece of a much larger puzzle.
What Truly Determines Health? An Uneven Split
Source: Adapted from County Health Rankings & Roadmaps model.
This model reveals a humbling truth: the vast majority of factors that determine whether a patient like Mr. Harris will be healthy or sick exist outside of our direct clinical control. Therefore, a pharmacy operation designed only for clinical and financial excellence, without considering the 90% of a patient’s life lived outside our walls, is an operation designed for failure. To truly impact patient outcomes, reduce readmissions, and fulfill our social mission, we must expand our operational lens. We must learn to see, screen for, and build systems to help mitigate the social barriers our patients face. This section is your foundational guide to doing exactly that.
Retail Pharmacist Analogy: The Home Inspector vs. The Building Architect
Imagine a patient comes to you complaining about a persistent medication side effect, like a cough from lisinopril. Your traditional role, honed over years of practice, is that of a master home inspector. You are called in to diagnose a specific problem in a specific “room” of the house. You expertly examine the room (the patient’s clinical profile), check the wiring (their kidney function), inspect the paint (look for allergies), and correctly identify the problem: the lisinopril is causing the cough. Your recommendation is to “renovate the room”—switch the patient to an ARB like losartan. You have solved the immediate problem, and the home inspector’s job is done.
Now, imagine the same patient comes back, but this time their problem isn’t a side effect; it’s non-adherence. They simply aren’t taking their new losartan. As a home inspector, you check the room again. Is the copay too high? Is the patient confused about the directions? You find no immediate problems in the room itself.
Adopting an SDOH-aware mindset transforms you from a home inspector into a building architect. An architect understands that the problem with a room is often not in the room at all. They look at the building’s blueprints. They discover that while the room is perfectly fine, the building’s foundation is cracked (housing instability), the water has been shut off (food and utility insecurity), and the elevator is broken, making it impossible for the resident to leave the 10th floor to get to the store (transportation barriers). The architect realizes that fixing the room is pointless until you fix the fundamental structural failures of the building and its connection to the surrounding city infrastructure.
As a pharmacy leader, your job is to become that architect. You must train your team to look beyond the immediate clinical “room” and ask about the patient’s foundation. You must design systems, not just to renovate rooms, but to provide support for the entire structure—connecting patients with resources that can repair their foundation, turn their water back on, and fix their elevator. Only then will the “room” you so carefully designed—the medication regimen—be a place where they can truly live and be well.
20.1.2 The Five Domains of SDOH: A Deep Dive for Pharmacy Leaders
To move from theory to practice, we must deconstruct the broad concept of SDOH into its core, actionable components. The U.S. Department of Health and Human Services, through its Healthy People 2030 initiative, organizes SDOH into five key domains. As a pharmacy leader, you must develop fluency in each of these domains, understanding how they manifest in your patient population and how they create specific, tangible barriers to medication access and adherence. This section will provide a masterclass in each domain, translating abstract social concepts into the concrete realities you manage every day.
Domain 1: Economic Stability
Definition: This domain encompasses the financial resources that enable individuals and families to meet their basic needs. It includes factors like poverty, employment status, food security, and housing stability. For a patient, economic stability is the fundamental platform upon which all other health-related activities are built. Without it, the concept of managing a chronic disease is a luxury they often cannot afford.
Direct Impact on Pharmacy Operations: This is the SDOH domain you and your team likely encounter most frequently, even if you don’t label it as such. It manifests as medication non-adherence due to cost, delayed prescription pickups, and patients asking which of their prescribed medications they can “do without” this month. It directly impacts your pharmacy’s revenue, adherence scores (like PDC/MPR), and contributes significantly to preventable hospital readmissions when patients are forced to choose between their medications and other essential needs.
Masterclass Table: Deconstructing Economic Instability in Pharmacy Practice
| SDOH Barrier | Patient Presentation / Red Flag | Traditional (Incorrect) Assumption | SDOH-Informed (Correct) Inquiry | Potential Operational Intervention |
|---|---|---|---|---|
| Medication Affordability / High Copayments | A patient with a new prescription for a DOAC (e.g., Eliquis) never picks it up after it’s sent from the ED. The refill history for their other chronic meds is sporadic. | “The patient is non-compliant and doesn’t understand the risk of stroke. They need more education.” | “I see this is a new and expensive medication. Sometimes the first copay can be a surprise. Are you having any trouble affording this one?” |
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| Food Insecurity | A diabetic patient’s A1c is consistently high despite being on multiple medications. Their glucose logs show extreme variability, with frequent hypoglycemia. | “The patient is not following their diet and is likely eating poorly.” | “Managing diabetes can be so tough, and it’s even harder when it’s difficult to get the right kinds of food. Do you ever find that you have to skip meals or run out of food before the end of the month?” |
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| Housing Instability / Homelessness | A patient frequently loses their medications, especially temperature-sensitive ones like insulin. They provide different contact addresses or have no stable address on file. | “This patient is irresponsible and careless with their medications.” | “It can be really hard to keep track of everything, especially medications that need to be refrigerated. Do you have a consistent and safe place to store your things right now?” |
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| Unemployment / Underemployment | A patient loses their commercial insurance and becomes uninsured, leading to a sudden halt in all medication refills. They express anxiety about an upcoming surgery. | “The patient needs to sign up for new insurance. We can’t fill these until they do.” | “I’m so sorry to hear about your job situation; that’s incredibly stressful. Let’s not worry about the insurance just yet. We have a team that can help you apply for emergency Medicaid and see if you qualify for our hospital’s charity care program. Let’s focus on getting you a bridge supply of your most critical medications today.” |
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Domain 2: Education Access and Quality
Definition: This domain relates to an individual’s educational background and the quality of that education, with a strong focus on literacy and, more specifically, health literacy. Health literacy is the degree to which individuals have the ability to find, understand, and use information and services to inform health-related decisions and actions for themselves and others. It is a stronger predictor of health status than age, income, employment status, education level, or race.
Direct Impact on Pharmacy Operations: Low health literacy is a silent epidemic that profoundly impacts every aspect of your operations. It leads to medication errors, poor adherence due to misunderstanding, failed comprehension of discharge instructions, and an inability to navigate the complex healthcare system. It makes programs like Medication Therapy Management (MTM) ineffective if the patient cannot understand the concepts being discussed. For a pharmacy leader, addressing health literacy is a cornerstone of patient safety and quality improvement.
Masterclass Table: Identifying and Mitigating Low Health Literacy
| SDOH Barrier | Patient Presentation / Red Flag | Traditional (Incorrect) Assumption | SDOH-Informed (Correct) Inquiry | Potential Operational Intervention |
|---|---|---|---|---|
| Low Health Literacy (Reading/Numeracy) | A patient with a new, complex warfarin regimen repeatedly has INRs out of range. When asked how they take it, they say “I take the white pill every day.” They cannot explain their dosing schedule. | “The patient is confused or forgetful. They are not capable of managing their own warfarin.” | (Using the “teach-back” method) “This can be a tricky medicine. To make sure I did a good job explaining, can you tell me in your own words how you are going to take your warfarin this week?” |
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| Language Barriers | A patient who speaks limited English is discharged with five new medications. Their family member translates, but seems unsure. The patient nods but does not ask questions. | “The family translated, so the patient understands. We’ve done our job.” | “Thank you so much for helping translate. To ensure we are all on the same page, I am going to call our hospital’s certified medical interpreter service so we can go through each medicine one more time together. It’s very important.” |
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| Lack of Digital Literacy / Access | An elderly patient is told to monitor their blood pressure and log it in the hospital’s patient portal. They consistently fail to do so and seem distressed when asked about it. | “The patient refuses to engage with our digital health tools.” | “I know this portal can be a bit confusing to set up. Do you have a smartphone or computer at home that you use regularly? Would you like me to connect you with someone who can walk you through it step-by-step or give you a paper log instead?” |
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Domain 3: Health Care Access and Quality
Definition: This domain focuses on the ability to access and receive high-quality health care services. This includes not just insurance coverage, but also the availability of providers, the ability to physically get to appointments (transportation), and receiving care that is competent, timely, and culturally sensitive.
Direct Impact on Pharmacy Operations: Barriers in this domain often mean the pharmacy becomes the only accessible healthcare touchpoint for a patient. A patient who cannot get a primary care appointment will come to the pharmacy for advice. A patient without transportation will delay picking up a critical antibiotic. Furthermore, “pharmacy deserts”—areas with few or no pharmacies—are a major public health issue. As a leader, your operational decisions about where to locate services, what hours to maintain, and how to facilitate access can either alleviate or exacerbate these barriers.
Masterclass Table: Overcoming Barriers to Health Care Access
| SDOH Barrier | Patient Presentation / Red Flag | Traditional (Incorrect) Assumption | SDOH-Informed (Correct) Inquiry | Potential Operational Intervention |
|---|---|---|---|---|
| Transportation Barriers | A post-operative patient’s family member calls to say they can’t pick up their prescribed pain medication until tomorrow, as they rely on a neighbor for rides. | “That’s unfortunate, but our policy is that we can’t deliver controlled substances. They will have to wait.” | “I understand completely; getting around can be very difficult. Let me check on a few options. We partner with a courier service for situations just like this. Let me see if we can arrange a delivery for you this afternoon.” |
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| Lack of a Primary Care Provider (PCP) | A patient frequently uses the ED for medication refills for chronic conditions like hypertension. They have no PCP listed in their chart. | “This is an inappropriate use of the ED and a waste of resources.” | “I see you’re having trouble getting your blood pressure medication refilled. It looks like you don’t have a regular doctor right now. Would you be open to me connecting you with our clinic’s scheduling team? They can help you find a primary care doctor who can manage these for you long-term.” |
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| Geographic Barriers (Pharmacy Deserts) | A patient discharged from your urban academic medical center lives in a rural county 60 miles away with no 24-hour pharmacy. They need a specialty medication that must be started immediately. | “The patient will have to figure out how to get their medication from a local pharmacy when they get home.” | “I see that getting this medication where you live might be a challenge. Let’s solve this before you leave. We can either provide you with the first fill from our outpatient pharmacy today, or I can call a pharmacy near your home to ensure they have it in stock and arrange for a family member to pick it up.” |
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Domain 4: Neighborhood and Built Environment
Definition: This domain refers to the physical characteristics of the neighborhoods where people live. This includes the quality of housing, access to healthy foods (food deserts), air and water quality, and the presence of crime and violence. The built environment can either promote health by providing safe spaces for recreation and access to nutritious food, or it can harm health through exposure to toxins, violence, and stress.
Direct Impact on Pharmacy Operations: This domain can seem distant from pharmacy, but its effects are profound. A child whose asthma is constantly exacerbated by mold in their apartment will be a frequent user of albuterol and oral steroids, driving up costs and leading to poor outcomes. A patient who cannot safely walk in their neighborhood cannot follow lifestyle advice for managing diabetes or hypertension. As a leader, understanding these environmental drivers is key to understanding the root causes of treatment failure for many common diseases.
Masterclass Table: Linking Environment to Medication Outcomes
| SDOH Barrier | Patient Presentation / Red Flag | Traditional (Incorrect) Assumption | SDOH-Informed (Correct) Inquiry | Potential Operational Intervention |
|---|---|---|---|---|
| Poor Housing Quality (e.g., mold, pests) | A pediatric patient with asthma has frequent ED visits for exacerbations despite being on appropriate controller medications. | “The parents are not administering the controller inhaler correctly. The child’s asthma is just severe.” | “It must be so frustrating to see your child struggling to breathe even with the medications. Sometimes, things in the home environment, like dust, mold, or pests, can trigger asthma. Have you noticed any of these issues where you live?” |
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| Food Deserts | A patient with newly diagnosed hypertension is counseled on the DASH diet. At their follow-up, their blood pressure is unimproved, and they admit to eating mostly canned and processed foods. | “The patient is unmotivated and not following the dietary advice.” | “The DASH diet is a big change, and it can be especially hard if fresh fruits and vegetables aren’t easy to find or afford nearby. What are the grocery shopping options like in your neighborhood?” |
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| Unsafe Neighborhoods | An obese patient with diabetes is strongly advised to begin a walking program. They agree but show no improvement in weight or A1c, and their activity logs are empty. | “The patient is lazy and not following the exercise plan.” | “Starting a new exercise routine is tough. I’m wondering what it’s like to go for a walk in your neighborhood. Do you generally feel safe being outside, especially in the evenings?” |
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Domain 5: Social and Community Context
Definition: This domain refers to the relationships and interactions people have with their family, friends, co-workers, and community members. It includes social cohesion, civic participation, experiences of discrimination and racism, and interactions with the justice system. A strong social support network is a powerful protective factor for health, while discrimination and isolation are potent drivers of stress and poor health outcomes.
Direct Impact on Pharmacy Operations: The effects of this domain are often subtle but powerful. An elderly patient living alone may be more prone to medication errors than one with an engaged caregiver. A patient who has experienced discrimination in healthcare settings may be mistrustful and less likely to adhere to recommendations. As a leader, building a culture of trust, empathy, and cultural humility within your team is a direct operational response to the challenges in this domain. It is about creating a safe and welcoming space for every patient, regardless of their background.
Masterclass Table: Navigating the Social and Community Context
| SDOH Barrier | Patient Presentation / Red Flag | Traditional (Incorrect) Assumption | SDOH-Informed (Correct) Inquiry | Potential Operational Intervention |
|---|---|---|---|---|
| Social Isolation | An elderly patient is discharged with a complex medication regimen. They seem overwhelmed and repeatedly ask the same questions. They live alone. | “The patient has poor memory and is probably going to be non-compliant.” | “This is a lot of new information to take in all at once, and it can be tough to manage on your own. Do you have any family or friends who help you with your medications? Would you be interested in our ‘medication buddy’ volunteer program or a weekly check-in call from our pharmacy?” |
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| Perceived Discrimination / Mistrust | A patient from a minority group is unusually quiet, avoids eye contact, and asks very few questions during a counseling session. They seem skeptical of the information provided. | “The patient is uninterested or disengaged.” | “I want to make sure I’m answering all of your questions and that you feel comfortable with this plan. Is there anything I’ve said that is unclear, or anything you’re worried about with this new medication?” (Ensure tone is open, non-defensive, and patient-centered). |
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| Caregiver Stress | The daughter of a patient with Alzheimer’s seems exhausted and irritable when picking up her mother’s prescriptions. She mentions she’s struggling to get her mother to take her pills. | “This caregiver has a bad attitude and isn’t trying hard enough.” | “It sounds incredibly challenging to manage everything. You are doing so much. I can only imagine how stressful it is. Are there any ways we could make the medication part easier for you? Perhaps we could package them in daily blister packs?” |
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20.1.3 The Pharmacy Operations Manager’s Role: From Awareness to Action
Understanding the five domains of SDOH is the essential first step. However, for a leader, awareness without action is insufficient. Your role is to translate this knowledge into tangible, sustainable operational systems that actively identify and mitigate these barriers. This requires building a business case, implementing new workflows, and forging partnerships outside the traditional sphere of healthcare.
Mastery 1: Building the Business Case for Addressing SDOH
In a world of tight budgets, any new initiative must be justified financially. Fortunately, the business case for addressing SDOH is powerful. Interventions that improve medication adherence and reduce health disparities are not just ethically right; they are financially smart, especially in a healthcare system shifting towards value-based care. Your task is to connect the dots between social interventions and financial outcomes.
Connecting SDOH Interventions to Your Bottom Line
- Reducing Hospital Readmissions: A patient readmitted for a heart failure exacerbation because they couldn’t afford their diuretic is a direct, measurable cost to the hospital, especially under programs like the Hospital Readmissions Reduction Program (HRRP). Your Argument: “Investing $10,000 in a robust medication assistance program that prevents just two or three readmissions a year will provide a positive return on investment.”
- Improving HCAHPS and Patient Satisfaction Scores: Patients who feel seen, understood, and cared for as whole people report higher satisfaction. A meds-to-beds program that relieves the stress of post-discharge pharmacy visits is a powerful driver of patient loyalty and positive survey responses. Your Argument: “A comprehensive discharge counseling process that screens for SDOH and provides solutions will directly improve our HCAHPS scores, impacting our value-based purchasing reimbursement.”
- Increasing Pharmacy Capture Rate and Revenue: A patient who can’t get to your pharmacy can’t fill their prescription there. A robust meds-to-beds and home delivery service not only addresses a key SDOH barrier but also directly captures prescription volume that would otherwise be lost to outside pharmacies. Your Argument: “By investing in a delivery van and driver, we can not only serve our most vulnerable patients but also capture an estimated X% of discharge prescriptions, generating Y in new annual revenue.”
- Succeeding in Value-Based Contracts: Accountable Care Organizations (ACOs) and other value-based models reward providers for keeping populations healthy and reducing total cost of care. Addressing SDOH is fundamental to achieving these goals. Your Argument: “As our health system takes on more financial risk, our ability to manage the social drivers of health in our highest-risk patients is no longer optional. The pharmacy is the most frequent touchpoint and is perfectly positioned to lead this effort.”
Mastery 2: Implementing SDOH Screening in Pharmacy Workflows
You cannot solve a problem you do not measure. Systematically screening for social needs is the first step in building an operational response. The goal is to make this screening a routine, non-disruptive part of the pharmacy workflow, integrated into key patient interactions.
| Workflow | Screening Opportunity | Key Questions (using a conversational approach) |
|---|---|---|
| Inpatient: Discharge Counseling | This is the most critical time to screen. The patient is about to transition from a controlled environment to the one where SDOH barriers are most potent. |
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| Outpatient: New Patient Intake | When a patient establishes care with your specialty or ambulatory care pharmacy, it’s the ideal time to get a baseline understanding of their social context. |
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| Community/Retail: MTM or Adherence Counseling | When a patient’s adherence scores are low, instead of assuming forgetfulness, use it as a trigger to screen for root causes. |
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The Ethical Rule of Screening: Don’t Ask What You Can’t Address
It is ethically problematic and damaging to patient trust to screen for social needs if you have no system in place to act on the information. Before you implement a screening program, you must have a clear, up-to-date resource guide and a defined workflow for connecting patients to help. This could be an internal social worker, a financial navigator, or a partnership with a community-based organization. Starting to screen without a “closed-loop” referral process will only highlight problems without offering solutions, causing more distress for your patients and moral injury for your staff.